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Search Results for " lysophospholipid receptor "

20

Compounds

Cat No. Product Name Synonyms Targets
T2000 AM095 LPA Receptor , LPL Receptor
AM095 is a potent LPA1 receptor antagonist with IC50 values of 0.98 and 0.73 μM for recombinant human or mouse LPA1 respectively.
T17183 TY-52156 S1P Receptor , LPL Receptor
TY-52156 is an effective and selective S1P3 receptor antagonist (Ki: 110 nM).
T12821 S1PR1 modulator 1 LPL Receptor
S1PR1 modulator 1 is a selective inhibitor of S1PR1 with a pIC50 of 7.6.
T9464 CYM50358 LPL Receptor
N-(4-(aminomethyl)-2,6-dimethylphenyl)-5 is a potent, selective antagonist of the sphingosine-1-phosphate receptor 4 (S1P4). CYM50358 inhibits S1P4 with an IC50 of 25 nM.
T7360 GSK2018682 S1P Receptor , LPL Receptor
GSK2018682 is an agonist of sphingosine-1-phosphate receptor (s1p1) and (s1p5) agonist(pEC50s of 7.7 and 7.2,respectively).
T7393 ONO-7300243 LPA Receptor , LPL Receptor
ONO-7300243 is an antagonist of lysophosphatidic acid receptor 1 (LPA1; IC50 : 0.16 µM).
T6347 Ki16198 LPA Receptor , LPL Receptor
Ki16198 is the methyl ester of Ki16425, which is a LPA antagonist and inhibits LPA1- and LPA3-induced inositol phosphate production with Ki of 0.34 μM and 0.93 μM, respectively, shows weaker inhibition for LPA2, no activ...
T15629 JTE-013 Apoptosis , S1P Receptor , LPL Receptor
JTE-013 is an effective and specific antagonist of S1P2. JTE-013 suppresses the specific binding of radiolabeled S1P to human and rat S1P2 (IC50s: 17 nM and 22 nM, respectively).
TQ0227 Etrasimod APD334 S1P Receptor , LPL Receptor
Etrasimod (APD334) is a specific and orally available antagonist of the sphingosine-1-phosphate-1 (S1P1) receptor (IC50: 1.88 nM in CHO cells).
T22834 H2L 5765834 LPA Receptor , LPL Receptor
H2L 5765834 is a lysophosphatidic acid receptors antagonist
T22703 CYM-5520 CYM 5520 S1P Receptor , LPL Receptor
CYM-5520 is a noncompetitive allosteric agonist of S1P2
T28169 NIBR-0213 NIBR 0213 LPL Receptor
NIBR-0213, a potent and selective S1P(1) antagonist, has efficacy in experimental autoimmune encephalomyelitis.
T6108 Ki16425 Debio 0719 LPA Receptor , LPL Receptor
Ki16425 (Debio 0719) is a competitive, potent and reversible antagonist to LPA1, LPA2 and LPA3 with Ki of 0.34 μM, 6.5 μM and 0.93 μM, respectively.
T22101 ML-031 S1P Receptor
ML-031 activated S1P2 with an EC50 value of 1 μM in an S1P reporter assay.
T15032 CYM50308 S1P Receptor , LPL Receptor
CYM50308 is a high affinity agonist of sphingosine-1-phosphate receptor 4 (S1P4-R) (EC50: 56 nM). CYM50308 has no activity at S1P1-R, S1P2-R and S1P3-R subtypes at concentrations up to 25 μM and it shows 37-fold more sel...
T12086 Mocravimod hydrochloride KRP-203 Others , LPL Receptor
Mocravimod hydrochloride (KRP-203) is an effecitive and orally active agonist of sphingosine 1-phosphate receptor type 1(S1PR1).
T3258 Ponesimod ACT-128800 S1P Receptor , LPL Receptor
Ponesimod (ACT-128800) is an orally available sphingosine-1-phosphate receptor 1 (S1PR1, S1P1) agonist with potential immunomodulating activity.
T9699 TAK-615 LPA Receptor
TAK-615 is commonly used to study pulmonary fibrosis and is a negative allosteric modulator of LPA1 receptors.
T4031 S1p receptor agonist 1 S1p-receptor-agonist-1 S1P Receptor , LPL Receptor
S1p receptor agonist 1 (S1p-receptor-agonist-1) is an S1P receptor agonist.
T15031 CYM50260 Others , LPL Receptor
CYM50260 is a potent and exquisitely selective agonist of sphingosine-1-phosphate 4 receptor (S1P4-R, EC50= nM) with no activity against S1P1-R, S1P2-R, S1P3-R and S1P5-R.
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TargetMol